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Paul M Lieberman Selected Research

Epstein-Barr Virus Nuclear Antigens

1/2021EBNA1 inhibitors have potent and selective antitumor activity in xenograft models of Epstein-Barr virus-associated gastric cancer.
10/2019Structural Basis for Cooperative Binding of EBNA1 to the Epstein-Barr Virus Dyad Symmetry Minimal Origin of Replication.
1/2016HCF1 and OCT2 Cooperate with EBNA1 To Enhance OriP-Dependent Transcription and Episome Maintenance of Latent Epstein-Barr Virus.
12/2010Development of drugs for Epstein-Barr virus using high-throughput in silico virtual screening.
10/2010Genome-wide analysis of host-chromosome binding sites for Epstein-Barr Virus Nuclear Antigen 1 (EBNA1).

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Paul M Lieberman Research Topics

Disease

26Neoplasms (Cancer)
03/2022 - 11/2008
15Latent Infection
01/2021 - 03/2010
12Infections
01/2021 - 11/2003
6Epstein-Barr Virus Infections
01/2020 - 11/2008
5Virus Diseases (Viral Diseases)
11/2021 - 03/2006
4Carcinoma (Carcinomatosis)
03/2022 - 01/2014
3Burkitt Lymphoma (Burkitt's Lymphoma)
01/2019 - 10/2010
2Nasopharyngeal Carcinoma
03/2022 - 01/2019
2Chromosomal Instability (Chromosome Stability)
06/2019 - 11/2011
2Kaposi Sarcoma (Kaposi's Sarcoma)
01/2018 - 07/2005
2Carcinogenesis
10/2017 - 08/2017
2Leukemia
01/2016 - 10/2015
2Herpesviridae Infections (Herpesvirus Infection)
10/2013 - 11/2011
2Pleural Effusion (Pleural Effusions)
05/2012 - 06/2006
2Lymphoma (Lymphomas)
05/2012 - 06/2006
1Primary Effusion Lymphoma
11/2020
1Autoimmune Diseases (Autoimmune Disease)
10/2019
1Hodgkin Disease (Hodgkin's Disease)
01/2019
1Melanoma (Melanoma, Malignant)
01/2018
1Glucose Metabolism Disorders
01/2018
1Hypoxia (Hypoxemia)
12/2016
1Genomic Instability
10/2016
1Medulloblastoma
09/2012
1Neoplasm Metastasis (Metastasis)
06/2010
1Retinoblastoma (Glioblastoma, Retinal)
03/2010
1variable Immunodeficiency syndrome
01/2010
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
06/2009
1Sickle Cell Anemia (Hemoglobin S Disease)
06/2009

Drug/Important Bio-Agent (IBA)

12ChromatinIBA
01/2021 - 07/2005
12Proteins (Proteins, Gene)FDA Link
10/2017 - 11/2003
10DNA (Deoxyribonucleic Acid)IBA
03/2022 - 03/2010
5Epstein-Barr Virus Nuclear AntigensIBA
01/2021 - 10/2010
4DNA-Binding Proteins (DNA Binding Protein)IBA
04/2020 - 04/2010
4Antiviral Agents (Antivirals)IBA
01/2020 - 11/2011
4Viral ProteinsIBA
10/2019 - 10/2017
4RNA (Ribonucleic Acid)IBA
01/2018 - 09/2012
3Transcription Factors (Transcription Factor)IBA
01/2021 - 06/2010
3EBV-encoded nuclear antigen 1IBA
04/2020 - 12/2010
3Histones (Histone)IBA
10/2019 - 12/2013
3CohesinsIBA
01/2017 - 03/2010
3Messenger RNA (mRNA)IBA
07/2014 - 03/2010
2latency-associated nuclear antigenIBA
01/2021 - 04/2020
2A-Form DNA (A-DNA)IBA
01/2019 - 07/2010
2Nuclear Antigens (Extractable Nuclear Antigens)IBA
01/2019 - 01/2016
2Telomerase (Telomerase Reverse Transcriptase)IBA
01/2018 - 09/2013
2Ganciclovir (Cytovene)FDA LinkGeneric
03/2014 - 04/2010
2Small Interfering RNA (siRNA)IBA
01/2014 - 06/2006
2NucleosidesIBA
10/2013 - 12/2010
2MicroRNAs (MicroRNA)IBA
03/2010 - 11/2008
1AntigensIBA
03/2022
1Biological ProductsIBA
11/2021
1Interferon Regulatory FactorsIBA
01/2021
1purineIBA
01/2021
1TAK-165IBA
11/2020
1manassantin BIBA
01/2020
1Mechanistic Target of Rapamycin Complex 2IBA
01/2020
1Fatty Acids (Saturated Fatty Acids)IBA
01/2019
1Transforming Growth Factors (Transforming Growth Factor)IBA
01/2019
1LipidsIBA
01/2018
1alpha-2'-deoxythioguanosineIBA
01/2018
1AntioxidantsIBA
01/2018
1Glucose (Dextrose)FDA LinkGeneric
01/2018
1Prolyl Hydroxylases (Prolyl Hydroxylase)IBA
12/2016
1Oxygen (Dioxygen)IBA
12/2016
1Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA
10/2016
1Retroelements (Retrotransposon)IBA
10/2016
1Histone MethyltransferasesIBA
01/2016
1Biomarkers (Surrogate Marker)IBA
01/2016
1Histone Deacetylases (Histone Deacetylase)IBA
03/2014
1Histone Deacetylase InhibitorsIBA
03/2014
1Pharmaceutical PreparationsIBA
12/2010
1Membrane Proteins (Integral Membrane Proteins)IBA
12/2010
1EnzymesIBA
12/2010
1Oncogene Proteins (Oncogene Protein)IBA
10/2010
1DNA-Directed DNA Polymerase (Polymerases, DNA)IBA
04/2010
1Carrier Proteins (Binding Protein)IBA
03/2010
1TransferasesIBA
03/2010
1HeterochromatinIBA
01/2010
1Hydroxyurea (Hydrea)FDA LinkGeneric
06/2009
1imidazole mustard (BIC)IBA
11/2008
1NF-kappa B (NF-kB)IBA
11/2008
1RNA Precursors (Precursor, mRNA)IBA
11/2008
1Nucleosomes (Nucleosome)IBA
11/2003

Therapy/Procedure

5Therapeutics
11/2020 - 12/2010
1Immunotherapy
03/2022
1Drug Therapy (Chemotherapy)
06/2009